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10.1111/cpr.13621 93 LiQ.LiaoJ.ChenW.ZhangK.LiH.MaF.et al (2022)

However, its use in PCOS is considered off-label. This means that it hasnt been FDA-approved for this condition

Clinical Risks and Considerations of Hormone Replacement Therapy The case for combining HRT and GLP-1 receptor agonists is, as the preceding sections have established, biologically compelling

Critics point out that the peptides for sale are often imperfect synthetics and are taken at doses much higher than any peptides in the body, raising the risk of allergic reactions and other harms

It could potentially help or cause a flare-up, so any research in this context must be done with extreme care and monitoring