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Pharmacokinetics, Dosing Frequency, and Circadian Exposure GLP-1 receptor agonists differ meaningfully in pharmacokinetics, central engagement, and downstream effects on feeding behavior, with potential implications for chronometabolic regulation [74]

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While Camilleri (2012) and Touny (2022) used prolonged monitoring periods of weeks or months to evaluate long-term effects, Hellstrm (2008) study had no follow-up following the treatment period

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