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Compatibility with common autoimmune medications The ACR Convergence 2025 data specifically showed benefit when GLP-1 agonists were added to existing DMARD therapy in RA patients

The law (Medicare Modernization Act of 2003) explicitly excludes drugs when used for weight loss, weight gain, or anorexia. (ASPE) Some proposed changes (including reinterpreting the exclusion for obesity) were considered , but in April 2025 those were not finalized