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Oral Supplements: Convenient but Slower Absorption Oral Vitamin B12 supplements are available in tablet, capsule, or liquid form and easily integrate into your daily routine

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The standard regimen involves: Loading doses without neurological involvement : 1 mg intramuscularly three times a week for 2 weeks [3] [8] Loading doses with neurological involvement : 1 mg intramuscularly on alternate days until no further improvement [3] [8] Maintenance therapy : 1 mg every 23 months for life in cases of pernicious anaemia or irreversible malabsorption (every 2 months if neurological involvement) [3] [8] This aggressive approach aims to prevent irreversible neurological damage, though recovery of established neuropathy may be incomplete, particularly if treatment is delayed

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in Nature Medicine found that NNMT inhibition in white adipose tissue increased energy expenditure and reduced fat mass in animal models without altering food intake or physical activity (Kraus et al., Nature Medicine )