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It reads pathway-level variants in FTO, GLP1R, MC4R, and TCF7L2 that describe baseline GLP-1 and energy-balance biology upstream context that applies to both compounds rather than a recommendation for one over the other
It stimulates insulin secretion, inhibits glucagon release, and slows gastric emptying, thereby reducing blood sugar levels post-meal
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Participants also completed questionnaires assessing diabetes distress (Problem Areas in Diabetes Teen [PAID-T]), hypoglycaemia fear (Hypoglycaemia Fear Survey [HFS]), and closed-loop treatment satisfaction (INsulin Dosing Systems: Perceptions, Ideas, Reflections, and Expectations [INSPIRE])