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NCT06383390: dedicated cardiac effects study A clinical trial specifically designed to study the cardiac effects of retatrutide is registered on ClinicalTrials.gov

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By avoiding the growth hormone receptor/IGF-1 pathway entirely, AOD-9604 eliminates the appetite-modulating effects that make growth hormone therapy challenging for weight management

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Notably, Saxenda is not recommended for individuals younger than 18 or older than 75, pregnant or breastfeeding women, those with a family history of certain types of cancer, or people with underlying kidney, liver, intestinal, or stomach diseases