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My first month, I lost 15 pounds. Some people struggle to tolerate the side effects of GLP-1 agonists

Severe cases of homocystinuria are typically caused by autosomal recessive genetic defects and exhibit characteristic clinical features including ocular lens dislocation, marfanoid features and other skeletal abnormalities including osteoporosis, intellectual disability, and thromboembolic disease, the latter frequently being the cause of premature death in affected individuals (28)

Arch Ital Urol Androl 2010

This high demand is behind nationwide shortages that have been happening since 2022 and are expected to last throughout 2024

But there are no exact numbers on how often it happens in people taking GLP-1 drugs