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Liquid chromatography combined with mass spectrometry allows both separation and molecular identification of peptide species

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The 24 individuals with obesity were taking a maintenance dose of GLP-1RA medication for weight loss ( N = 14, GLP-1RA group) for at least 30 days, or not taking any medication for weight loss ( N = 10, control group)

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In a surgically induced-OA model in rats, liraglutide also attenuated rat cartilage degeneration through suppressing the release of inflammatory mediators and protected chondrocytes against endoplasmic reticulum (ER) stress and apoptosis induced by interleukin-1 (IL-1) or triglycerides [46]