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" Yes, that's exactly my suspicion - that more frequent, lower doses could end up being more effective than the large doses that are standard at the moment

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Expression of apoplast-targeted plant defensin MtDef4.2 confers resistance to leaf rust pathogen Puccinia triticina but does not affect mycorrhizal symbiosis in transgenic wheat

The main benefit was the absence of side effects in those using myo-inositol ( Metformin and myo-inositol in women with PCOS 2019 )