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A Mendelian randomization study in Frontiers in Endocrinology found that genetically predicted higher insulin resistance was associated with worse cognitive performance, with changes in brain cortical structure mediating part of the effect
& Russell, J
Abdulmalik et al., demonstrated a significantly increased expression of collagen and sulfated glycosaminoglycans (s-GAG), as well as the expression of tendon-specific genes, in Ex-4-treated hMSC compared to both untreated and insulin-treated controls [14]
Fluoxetine and sertraline are among the SSRIs least associated with weight gain, and fluoxetine may cause modest initial weight loss in some patients
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