newest glp-1 medications for type 2 diabetes 2025 like Ozempic, Wegovy and Mounjaro are changing and weight management, but they aren't recommended during pregnancy or while nursing. The current recommendation is to stop before conception and discuss glp-1 agonist drugs New Guidelines

Injection site reactions (erythema, pruritus, swelling) occur in 1.4-2.4% of patients using subcutaneous formulations and are well-documented, localized effects

Garolla A, Pizzol D, Carosso AR, et al

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Finally, exendin-4-induced activation of both WT and V229A GLP-1R tended to reduce the diffusion of lipids at the plasma membrane labelled with the environmentally sensitive Laurdan probe (34) (Figure 4D), with no differences in Laurdan lateral diffusion between WT and V229A