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However, it is likely that the activation of ERK1/2 by AA is an indirect effect dependent on a short and regulated imbalance of the intracellular redox state that would promote the presence of Ras-GTP and the consequent activation downstream of the protein kinase pathway activated by mitogens (MAPK) (Salazar et al., 2016)

*Correspondence: Marc Diederich, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, South Korea e-mail: [email protected] Michael Schnekenburger, Tommy Karius, and Marc Diederich have contributed equally to this work

Taurine improves insulin sensitivity in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous type 2 diabetes

Sangsuwan W, Asawanonda P

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