18.420.9%, with the 10 mg and 15 mg, along with improvements in cardiometabolic risk factors [118,119,120]
Listed effects of GLP-1 include: 1) reduced glucagon secretion from the liver (thereby slowing down the release of glucose, or blood sugar, into the bloodstream during periods of fasting or reduced food intake), 2) increased insulin production, 3) decreased appetite, and 4) decreased intestinal motility (causing food to move slower through the digestive system, thereby further improving blood sugar and reducing appetite)
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Targeting inflammatory pathways, specifically the NLR family pyrin domain containing 3 (NLRP3)/IL-1/IL6/C-reactive protein (CRP) pathway, has emerged as another strategy for improving cardiorenal outcomes in high-risk populations