These rashes are often localised and can develop as the body adjusts to the medication
It also slows gastric emptying and reduces appetite, which can lead to weight loss
sometimes increases in HDL Liver : Improvements in fatty liver disease (reduced liver fat, improved liver enzymes) Cardiovascular Improvements : Blood Pressure : Significant reductions in systolic and diastolic blood pressure Cardiovascular Events : According to SELECT trial (semaglutide), 20% reduction in major cardiovascular events (heart attack, stroke, cardiovascular death) Heart Function : Improvements in cardiac structure and function markers Physical Function Improvements : Mobility : Improved ability to walk, climb stairs, engage in physical activities Joint Pain : Reduced knee, hip, and back pain from decreased weight-bearing stress Sleep : Improvements in sleep quality
Consequently, treatment guidelines for IBD and rheumatic diseases have been adapted accordingly and include TNF- inhibitors in their recommendations, making TNF- inhibitors an important option in the therapeutic landscape
Over a mean follow-up period of 2.4 years, 0.2% of the GLP-1 receptor agonist cohort progressed to wet AMD compared with only 0.1% of control participants, resulting in an increased hazard for wet AMD of 2.21 for the GLP-1 RA cohort
