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Key findings: Prescribing trends Using a subset of real-world electronic health record (EHR) data from Truveta, Truveta Research identified people who were prescribed a GLP-1 RA between January 01, 2018 and December 31, 2024

Earlier generations of GLP-1 medicines such as exenatide, liraglutide, dulaglutide, and semaglutide function solely as GLP-1 receptor (GLP-1R) agonists

While compounding pharmacies were temporarily permitted to create semaglutide formulations similar to Ozempic, they must stop production now that the Ozempic and Wegovy shortage has been lifted

Casey BM, Thom EA, Peaceman AM, Varner MW, Sorokin Y, Hirtz DG, Reddy UM, Wapner RJ, Thorp JM, Saade G, Tita ATN, Rouse DJ, Sibai B, Iams JD, Mercer BM, Tolosa J, Caritis SN, VanDorsten JP

As we mentioned, IGF-1 is strongly associated with hyperplasia (new cell creation)