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A recent study found that certain GIPR genetic variants that impair both Gs and beta-arrestin 2 recruitment are linked to lower adiposity 38 , suggesting that GIPR effects on body weight involve complex signalling pathways

Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy

Wetli, H

Indirect network meta-analyses rank retatrutide highly, but that is cross-trial inference, not a direct win