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Retatrutide is an investigational triple incretin receptor agonist acting on GLP-1, GIP, and glucagon receptors currently undergoing clinical trials for the treatment of obesity and type 2 diabetes

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It is possible that the LKB1/AMPK/ACC pathway is activated by direct redox modulation of cellular proteins since activation of AMPK pathway has been directly linked to cellular redox status and hydrogen peroxide 49

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