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10.1016/j.cobeha.2019.01.011 26

Species differences in peptide metabolism, receptor density, and clearance pathways mean that a compound safe in rats could, in theory, produce unexpected toxicity in humans

For instance, liposomal polyvinylpyrrolidone (PVP)-iodine hydrogel formulations have been investigated for the treatment of impetigo contagiosa and related infective dermatoses, offering extended and controlled drug release profiles that may enhance both therapeutic efficacy and patient compliance [206]