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"These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones," says Jena Shaw Tronieri, Senior Research Investigator at Penn's Center for Weight and Eating Disorders and a co-author of the study

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These facilities use FDA-approved active pharmaceutical ingredients (semaglutide and tirzepatide) combined under strict quality and sterility standards equivalent to commercial manufacturing

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But it eliminates the combination for these individuals