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It is used in metabolic signaling research, energy homeostasis studies, and multi-hormonal pathway investigations

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Initial efforts involved synthesizing AngIV analogs with extended half-lives by incorporating reduced peptide bonds between residues, as exemplified by Divalinal-AngIV and Norleural-AngIV

Endocrinology 141(6):19361941 Tibble CA, Cavaiola TS, Henry RR (2013) Longer acting GLP-1 receptor agonists and the potential for improved cardiovascular outcomes: a review of current literature