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This stabilized form resists degradation and significantly reduces the production of ammonia, even during prolonged incubation at 37C (Figure 2)

The oxidative metabolism of EtOH by alcohol dehydrogenase (ADH) and cytochrome P450 2E1 (CYP2E1) leads to the rapid accumulation of NADH, changing the NAD + /NADH ratio, effectively downregulating FA oxidation and leading to a metabolic shift favoring FA synthesis (Donohue Jr., 2007)

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