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Highlights Retatrutide is a novel triple hormone receptor agonist that simultaneously targets GLP-1, GIP, and glucagon receptors to regulate appetite and energy expenditure

The fact that both approaches appear to enhance weight loss beyond GLP-1 agonism alone suggests that modulating GIP activity in either direction may be beneficial, potentially through different downstream mechanisms

Toxicokinetics, doseresponse, and risk assessment of nanomaterials: methodology, challenges, and future perspectives

Use of naloxone in valproic acid overdose: case report and review

l-Citrulline Supplementation-Increased Skeletal Muscle PGC-1 Expression Is Associated with Exercise Performance and Increased Skeletal Muscle Weight