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Common Side Effects Both medications cause primarily gastrointestinal effects: Saxenda common side effects: Nausea (39%) Diarrhea (21%) Constipation (19%) Vomiting (16%) Injection site reactions (14%) Headache (14%) Dyspepsia (10%) Semaglutide common side effects: Nausea (44%) Diarrhea (30%) Vomiting (24%) Constipation (24%) Abdominal pain (20%) Headache (14%) Fatigue (11%) Side Effect Comparison Table Interpreting the Numbers Semaglutide appears to have higher rates of GI side effects in clinical trials

5 to 15 mg/week), supplemental curcumin (1,000 mg/day) for six weeks increased the antidepressant effect of the medication (104)

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424 In AD, GLP-1(7-36) amide inhibits IL-1 transcription and prevents cognitive dysfunction, amyloid precursor protein synthesis, and cell death