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If a severe deficiency is found, a loading dose phase may be recommended, consisting of weekly injections for the first month

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N Engl J Med (2016) 375:174955

Subcutaneous injections offer significantly superior bioavailability compared to topical application, allowing GHK-Cu to reach deeper tissue layers and exert systemic effects that benefit not only the skin but also hair follicles and broader tissue remodeling internally

Kondisi ini ditandai dengan kerontokan rambut, perubahan pada kuku, kulit menjadi kering dan pecah-pecah