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These macrophages, when activated by TLR ligands and interferon-, release proinflammatory cytokines such as TNF- and IL-6, which contribute to the progression of MASLD and systemic IR by modulating other immune cells (64) (Table 1)

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pseudomallei via oral supplementation of NAC in diabetic patients resulted in only an increase in free GSH and GSSG but not the overall GSH:GSSG ratio [104]