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Pharmacological inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle

If you are already at 4mg or higher and not noticing changes, factors like diet composition, sleep quality, stress, and individual biology may be influencing your response

Following MTX injection (in physiological saline, 20 mg/kg, single dose), either saline (MTX group, n 8) or WPC (2 g/kg, oral gavage, MTX + WPC group

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