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If youre already on medication for diabetes like metformin or insulin, talk to your doctor about the best time to add in a GLP-1

Weight loss on Wegovy In the STEP UP trial, participants taking the maximum dose of Wegovy, 7.2mg, (semaglutide) lost an average of 20.7% of their body weight over 72 weeks

Huang J, Xue S, Teixeira AP, Fussenegger M (2024) A Gene-Switch Platform Interfacing with Reactive Oxygen Species Enables Transcription Fine-Tuning by Soluble and Volatile Pharmacologics and Food Additives

Although these treatments involving keratolytic agents appear effective, they do not cure the skin condition

In another trial, sotagliflozin, which can inhibit both SGLT2 and SGLT1, added to insulin significantly lowered HbA1c, systolic blood pressure, and body weight, and required significantly less daily insulin compared to placebo [66]