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A 12-week study in which patients diagnosed with T2DM were treated with the DPPIV inhibitor, sitagliptin, revealed increased serum levels of PYY 1-36 and improvement of glucose and non-glucose dependent insulin secretion 71

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Instead, the GSTO2 rs2297235 AG genotype, which leads to increased expression of GSTO2 , is significantly associated with age-at-onset of spinocerebellar ataxia type 2 (SCA2) 58