labial melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Living with Labial Melanotic Macule:

Genetics Society of America/Oxford University Press (OUP): 13631375

MMPs are considered to play a crucial role in the degradation of the extracellular matrix, and their activity is posited to be intricately balanced with TIMPs

The only downside is its a bit pricey

In general, B12 injections provide the best results for: Individuals with a B12 deficiency People experiencing fatigue thats hindering their activity level Those following low-calorie or plant-based diets that may lack sufficient B12 If youre considering adding B12 shots to your weight loss plan, youll need to consult with your primary doctor to determine the right dosage and frequency for your goals

The economic equation shifts for longer-term use