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The mtGSH maintains mitochondrial integrity and promotes adaptive survival responses induced by prolonged cytoplasmic GSH loss, including upregulation of anti-apoptotic proteins such as BCL2 37,38

Synaptic transmission is modulated by glucagon-like peptide 1 and glucose-dependent insulinotropic peptide mimetics GLP-1 and GIP receptor agonists are peptide hormones and growth factors, and share the neuroprotective effects of NGF and BDNF

Furthermore, combined aerobic and resistance training decreases circulating ApoJ levels