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Since P2 receptors are upregulated as a consequence of ADA treatment we probed if ADA induced inflammation is dependent on P2 receptors

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Through diverse molecular mechanisms, it interferes with normal cellular processes such as transformation, senescence, programmed cell death, and proliferation, thereby directly contributing to the development of various human diseases (Table 3)

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Zepbound activates receptors of hormones secreted from the intestine (glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)) to reduce appetite and food intake