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Male patients, conversely, showed more pronounced peroxisome dysfunction and severe mitochondrial lipid oxidative damage

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Consequently, the elevated levels of free radicals can damage cellular structures, resulting in the accumulation of cytotoxic substances and ultimately leading to the death of substantia nigra cells, thereby triggering the onset of PD ( 2.3.3 Neurological inflammation loop Neuroinflammation is a significant indicator of PD and plays a pivotal role in its pathogenesis and progression (Kubota et al., 2020)

Appetite Control: GLP-1, a popular peptide in weight loss therapy, mimics a hormone that regulates blood sugar and reduces hunger