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Unlike Zepbound pens (which are pre-filled with a needle inside), each Zepbound vial contains one dose of medication that is withdrawn from the vial using a syringe and then injected under the skin

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In a hospital-based case control study, Vogt et al

Long term outcomes still depend on lifestyle behaviors - - eating patterns, physical activity, adherence, coping strategies, and the ability to sustain changes over time

2024;doi:10.1056/NEJMoa2403347) demonstrated that addition of semaglutide (Ozempic/Wegovy, Novo Nordisk) to an SGLT2 inhibitor showed no renal protective effect (HR = 1.07, 95% CI 0.69-1.67), although the number of subjects receiving an SGLT2 (16%) in this study was relatively small