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My purpose here is to provide a broad overview of the mechanisms of glutathione-mediated conjugation of anticancer drugs

doi: 10.3389/fphar.2024.1491249 Received 04 September 2024 Accepted 14 November 2024 Published 02 December 2024 Volume 15 - 2024 Edited by Anna Maria Giudetti, University of Salento, Italy Reviewed by Daniele Vergara, University of Salento, Italy Azza Awad, Al-Azhar University, Egypt Updates Copyright 2024 Mahmoud, Elshazly, El-shaarawy, Zaitone, Aldahish, Ahmed, Fawzy, Aloyouni, Abed, Saeedi and El-Sayed

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This often occurs in smokers, people with metabolic disease, heavy alcohol drinkers, as a side effect of certain prescription drugs, rheumatoid arthritis and impaired thyroid function