how retatrutide works (not yet approved in US but people using anyway) promises even potentially greater weight loss amongst the GLP1 drugs. https://www.nejm.org/doi/full/10.1056/NEJMoa2301972 How to Inject Retatrutide Safely:

Today, the FDA is announcing its intent to take decisive steps to restrict GLP-1 active pharmaceutical ingredients intended for use in non-FDA-approved compounded drugs that are being mass-marketed by companies including Hims & Hers and other compounding pharmacies as similar alternatives to FDA-approved drugs

GLP-1 medications work by mimicking the natural hormone that reduces appetite, slows digestion so you feel full longer, and helps regulate blood sugar levels

no progestogen needed Timing of HRT initiation / strongest cardiovascular benefit when started within 10 years of menopause or before age 60 Key safety flag / any unscheduled uterine bleeding on combined HRT requires endometrial evaluation GLP-1 nausea overlap / both GLP-1 drugs and low estrogen cause nausea

In the medical world, this security guard or carrier molecule is referred to as SNAC

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