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High levels of saturated free fatty acids can cause ER stress that activates the UPR pathway by various mechanisms, such as inhibition of the enzyme that mobilizes ER Ca 2+ (i.e., ER Ca 2+ ATPase), activation of IP3 receptors, and/or directly impairing ER homeostasis (241)

The market growth is driven by the rising global prevalence of obesity, increased awareness of medical weight management solutions, and strong clinical outcomes supporting early adoption

Improved cardiometabolic health: Wegovy not only aids in weight reduction but also improves blood pressure, lipid profiles, and glycemic control