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[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Fang F.C

Key Nutrient Deficiencies That Contribute to Anxiety B Vitamins (B12, B6, and B9 - Folate) Vitamin B12 : Critical for the synthesis of neurotransmitters Deficiency causes neurological symptoms Affects myelin production Maintains nerve cell health Involved in the metabolism of homocysteine Vitamin B6 : Participates in the synthesis of serotonin Regulates dopamine levels Helps in the production of GABA Necessary for amino acid metabolism Supports immune function B9 (Folate) : Essential for DNA methylation Supports neurotransmitter production Regulates gene expression Involved in the synthesis of S-adenosylmethionine

doi: 10.1016/j.soilbio.2006.03.024 189 ShahidM.AhmedB.KhanM

For instance, with DXd, the active metabolite of DS-8201, studies have found loss-of-function mutations in the DNA repair-related gene SLX4 (an assembly scaffold protein for endonucleases) in tumors

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