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Eligibility Criteria Studies were eligible if they evaluated BPC-157, thymosin beta-4 or marketed derivatives (including TB-500), GHK-Cu, or other peptide-based agents commonly promoted for musculoskeletal healing or recovery and reported outcomes relevant to musculoskeletal pathology, orthopaedic surgery, postoperative recovery, or perioperative risk domains

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Remarkably, in a trial using high-dose thiamine for fatigue related to inflammatory bowel disease (IBD), the relative abundances of Faecalibacterium prausnitzii , a member of the Ruminococcacea family, and Roseburia hominis , a member of the Lachnospiraceae family, inversely correlate with fatigue severity both pre- and post-treatment with thiamine (62)