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A 2020 systematic review and meta-analysis published in Clinical Nutrition ESPEN (Asbaghi et al., pooling 12 randomized controlled trials) reported a statistically significant weighted mean reduction of 2.07kg in body weight, 0.47 kg/m in BMI, and 1.08cm in waist circumference compared to placebo
Shortly after, high-end retailer Marks & Spencer brought out its Nutrient Dense line of products, specifically targeting weight-loss drug users with high-fibre options
When appetite drops, food intake usually drops too, and that often means lower intake of sodium, potassium, and other minerals that help regulate hydration, nerve function, and muscle performance
For more persistent reflux, your GP may recommend: Proton pump inhibitors (PPIs) such as omeprazole or lansoprazole, which reduce stomach acid production and are the first-line treatment for GORD according to NICE guidance, typically for 4-8 weeks with review
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