Future metabolomic studies on senescent cells performed in vivo, or in culture but with a more controled environment, with physiological concentrations of nutrients, would allow a more accurate description of redox metabolism in senescence (Jang et al., 2018)
There were also noted improvements in markers of glycemic control and insulin sensitivity
Green PS, Mendez AJ, Jacob JS, Crowley JR, Growdon W, Hyman BT, et al
All kidney samples were collected at 24 h after CLP
A) Cells were stimulated for 15 min with GLP-1 936 amide at the concentrations indicated and either vehicle (KHB+5% DMSO) or compound 2 at the indicated concentrations in the presence of IBMX