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Therapeutic targeting of proteostasis in cancer Cancer cells are exposed to persistent proteotoxic stress driven by rapid proliferation, genomic instability, hypoxia, metabolic rewiring, and therapeutic pressure

During the period when semaglutide and tirzepatide were on the FDA shortage list, 503B compounding facilities were permitted to produce these medications legally

This timing is thought to support better absorption, especially for liposomal formulations, since food can interfere with how liposomes are absorbed

Based on available data, no major side effects or safety issues are currently reported