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Within the hypothalamus the activation of GHS-1Ra in NPY and AgRP neurons is required for the orexigenic responses exerted by ghrelin release from A (X-like) cells in the stomach

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doi: 10.1073/pnas.2309967120

The experimentation with GHK-Cu is associated with a tentative reduction in MDA levels and a possible restoration of GSH levels, suggesting a potential ameliorative action on oxidative stress