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The 90 mg cohort showed a more balanced profile with 11.1% weight loss (9.8% placebo-adjusted) and a 25% discontinuation rate, while the 60 mg and 30 mg cohorts delivered 8.7% (7.4% placebo-adjusted) and 7.0% (5.7% placebo-adjusted) weight loss, respectively, with discontinuations at 28% and 20%

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