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High doses simply result in expensive urine and potential stomach discomfort

however, these effects were reversed following GBA1 knockdown

Sogut S, Zoroglu SS, Ozyurt H, Yilmaz HR, Ozugurlu F, Sivash E, Yetkin O, Yanik M, Tutkun H, Savas HA: Changes in nitric oxide levels and antioxidant enzyme activities may have a role in the pathophysiological mechanisms involved in autism

31 Intravenous NAC therapy was reported to lead to complete remission in the case of a patient with IC/BPS for 26 years despite treatment with multiple therapies, but more studies are needed before IV NAC can be recommended as a therapy for IC/BPS