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Typically, the characteristic clinical presentation becomes more apparent in adulthood ( Hyperphagia in PWS is still not fully understood, and controlling appetite remains a challenge in managing these patients

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Possible reasons include Type 1 diabetes diagnosis, advanced Type 2 diabetes with severely depleted beta cells, contraindication to GLP-1 drugs (thyroid cancer history, pancreatitis history), insurance or cost barriers, prior GLP-1 intolerance, or very high blood sugar requiring immediate insulin coverage

Pomegranate Fruit is renowned for its high antioxidant content, particularly punicalagins and punicic acid, which help protect cells from oxidative stress and inflammation