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Despite this, insufficient vitamin B12 still remains a problem for some vegetarians and vegans

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While some people experience mild discomfort during the procedure, many clinics use cooling mechanisms or topical anesthetic creams to enhance comfort and reduce any potential pain

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Strong involvement of thiamine transporters in the differentiation of enterocytes is suggested by approximately 6-fold higher thiamine uptake, corresponding to elevated expression of SLC19A2 and SLC19A3, in the differentiated jejunum epithelial cells of the villi, compared to the non-differentiated jejunum epithelial cells of the crypt (152)