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It is widely studied in preclinical models for its role in cellular signaling, angiogenesis, and tissue-specific biological responses
The litigation continued to broaden in September 2025, with new lawsuits alleging additional gastrointestinal injuries such as ileus , and Eli Lilly filed a motion seeking to centralize federal vision-loss (NAION) claims within MDL 3094 or create a separate MDL under the same judge

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