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Materials and methods: Preadipocytes were isolated from SAT and VAT collected during the bariatric surgery from 8 severely obese donors (BMI 42.7 kg/m2, age 49.6 years, n = 2 men and n = 6 women) and differentiated into mature adipocytes over 14 days

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Since GLP-1 medications themselves can cause gastrointestinal side effects including nausea and altered bowel habits, individuals without a gallbladder may experience a compounding effect that requires careful dietary management and potentially slower dose titration according to the product's SmPC guidance

Different LC effect in the limbs may be associated with the higher rates of glycogenolysis during arm exercise at the same relative intensity as leg exercise [44]