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The current study only investigated male mice since they are more susceptible to diet-induced obesity and diet-induced insulin resistance than female mice ( After 12 weeks of treatment, glucose tolerance tests and metabolic measurements were carried out

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N Engl J Med 1990

As expected GPP3 was observed bound within the hydrophobic pocket of VP1, in an essentially identical conformation to that previously observed for this compound bound to plant expressed PV3-SC8 18 (Fig