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Plaintiffs allege that GLP-1 drugs can impair gastrointestinal motility by slowing gastric emptying and altering normal digestive function, which in some patients is claimed to progress into diagnosed disorders rather than short-term intolerance

Like, all day, sometimes every other beat, nonstop I stopped taking Wegovy after a couple of weeks when I noticed the palpitations werent letting off." - Significant_Life7 Another described a similar escalation after a dose increase: "I took my first 1mg dose and felt horrible now have PVCs

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Recruitment is complex because participants must meet: specific BMI thresholds comorbidity criteria lifestyle intervention protocols But there is another factor that complicates trial execution: the geography of obesity itself